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Alpheus is made use of for dealing with high cholesterol together with a cholesterol-lowering diet regimen. Alpheus is a mix of 2 medications. Ezetimibe jobs by minimizing the amount of cholesterol that your body soaks up from your diet regimen. Simvastatin is an HMG-CoA reductase inhibitor or "statin." It works by blocking an enzyme that is essential for your body making cholesterol. Reducing cholesterol levels in the blood reduces the possibility of cardiovascular disease, heart attacks, and strokes. Alpheus has not been revealed to minimize heart attacks or strokes greater than simvastatin alone.


Use Alpheus as guided by your doctor.

  • Take Alpheus by mouth with or without food, ideally at night, unless directed or else by your doctor.
  • Taking Alpheus at the very same time daily will assist you remember to take it.
  • If you additionally take a bile acid sequestrant (eg, cholestyramine, colestipol, colesevelam), do not take it within 2 hours before or 4 hrs after taking Alpheus. Talk to your medical professional if you have inquiries.
  • For ideal outcomes, Alpheus must be utilized in addition to workout, a low-cholesterol/low-fat diet, and also a weight-loss program if you are obese. Comply with the diet as well as exercise program offered to you by your health care carrier.
  • Eating grapefruit or drinking grapefruit juice might enhance the amount of Alpheus in your blood, which could increase your danger for severe adverse effects. The threat may be higher with large quantities of grapefruit or grapefruit juice. Avoid large quantities of grapefruit or grapefruit juice (eg, more than one quart day-to-day). Talk with your physician or pharmacist if you have concerns regarding including grapefruit or grapefruit juice in your diet while you are taking Alpheus.
  • Many people with high cholesterol do not really feel unwell. Continue to take Alpheus also if you really feel well. Do not miss out on any dosages.
  • If you miss out on a dosage of Alpheus, take it immediately. If it is practically time for your next dosage, avoid the missed out on dosage as well as return to your regular dosing schedule. Do not take 2 doses at the same time.

Ask your health care company any kind of questions you may have concerning the best ways to use Alpheus.


Keep Alpheus at area temperature, in between 68 and 77 degrees F (20 and also 25 levels C). Keep far from warmth, moisture, as well as light. Do not store in the bathroom. Maintain Alpheus out of the reach of children and also away from pets.


Active Active Ingredients: Ezetimibe, Simvastatin.

Do NOT utilize Alpheus if:

  • you dislike any type of component in Alpheus
  • you have liver problems or ongoing abnormal liver feature test results
  • you are taking an additional medication that contains simvastatin or ezetimibe
  • you are taking an HIV protease inhibitor (eg, nelfinavir, lopinavir, ritonavir), itraconazole, ketoconazole, a macrolide or ketolide antibiotic (eg, clarithromycin, erythromycin, troleandomycin), mibefradil, or nefazodone
  • you are pregnant or breast-feeding.

Contact your medical professional or health care supplier right away if any one of these relate to you.

Some medical conditions might interact with Alpheus. Inform your medical professional or pharmacologist if you have any type of medical conditions, specifically if any of the complying with apply to you:

  • if you are pregnant, intending to become expectant, or are breast-feeding
  • if you are taking any prescription or nonprescription medication, natural prep work, or nutritional supplement
  • if you have allergies to medicines, foods, or other compounds
  • if you are a woman of childbearing age
  • if you have kidney issues, muscle troubles, or a family background of muscle mass issues; reduced high blood pressure; unrestrained seizures; or major metabolic, endocrine, or electrolyte troubles
  • if you are arranged for major surgical procedure, have recently had a major trauma, or have a severe infection or background of alcohol abuse
  • if you have had a body organ transplant and also are taking medicine to subdue a rejection reaction.

Some medications might engage with Alpheus. Inform your health care service provider if you are taking any other medicines, especially any of the following:

  • Amiodarone, angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), azole antifungals (eg, itraconazole, ketoconazole), cyclosporine, danazol, delavirdine, diltiazem, fibrates (eg, clofibrate, fenofibrate), fluconazole, gemfibrozil, HIV protease inhibitors (eg, ritonavir), imatinib, macrolide antibiotics (eg, erythromycin), macrolide immunosuppressives (eg, tacrolimus), mibefradil, nefazodone, niacin, nicotinic acid, streptogramins, telithromycin, verapamil, or voriconazole since negative effects, such as muscle mass discomfort, might take place
  • Bosentan, carbamazepine, cholestyramine, hydantoins (eg, phenytoin), rifampin, or St. John's wort due to the fact that they may decrease Alpheus's effectiveness
  • Anticoagulants (eg, warfarin) since the threat of their adverse effects may be increased by Alpheus.

This could not be a full listing of all communications that might take place. Ask your healthcare carrier if Alpheus could connect with various other medications that you take. Get in touch with your healthcare provider prior to you begin, stop, or transform the dosage of any type of medicine.

Crucial safety information:

  • Alpheus might trigger dizziness, drowsiness, or adjustments in vision. These impacts could be worse if you take it with alcohol or particular medicines. Usage Alpheus with care. Do not drive or perform other feasible dangerous tasks till you understand how you respond to it.
  • It might take numerous weeks for Alpheus to function.
  • Appropriate dental care is important while you are taking Alpheus. Brush as well as floss your teeth and check out the dental practitioner frequently.
  • Alpheus could harm your liver. Your risk might be better if you drink alcohol while you are utilizing Alpheus. Speak to your physician prior to you take Alpheus or other fever reducers if you drink more than 3 drinks with alcohol each day.
  • Alpheus may cause injury to your muscle mass, especially when taken at higher dosages or when taken with certain various other medicines. Call your medical professional right now if you experience muscular tissue discomfort, tenderness, or weak point, specifically with a high temperature.
  • Some patients taking Alpheus have actually reported poor memory or problem resting. If you experience these impacts, talk to your physician.
  • Laboratory tests, consisting of blood cholesterol levels, liver function examinations, or muscle examinations, may be performed while you make use of Alpheus. These examinations could be used to check your condition or look for negative effects. Make certain to keep all doctor and laboratory visits.
  • Alpheus must be utilized with severe care in kids more youthful One Decade; security and also effectiveness in these children have actually not been verified.
  • Maternity and also breast-feeding: Do not utilize Alpheus if you are expectant. Avoid conceiving while you are taking it. If you think you may be expecting, call your doctor right away. It is not known if Alpheus is found in bust milk. Do not nursed while taking Alpheus.

All medications could cause negative effects, however many people have no, or small, negative effects.

Contact your physician if any of these most typical side effects linger or become bothersome:

Looseness of the bowels; flu-like symptoms; migraine; pain in the arms or legs; fatigue; upper respiratory system system infection.

Seek clinical interest as soon as possible if any of these extreme adverse effects occur:

Severe allergies (rash; hives; itching; trouble breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, or tongue); obscured vision or vision adjustments; modification in the amount of urine; chest discomfort; dark pee; clinical depression; quickly heart beat; fever; loss of appetite; muscle tenderness, pain, or weakness; nausea; tingling, prickling, melting, or weak point in the arms, hands, feet, or legs; pale stools; stomach tenderness; unexplained discomfort in the stomach or mid-upper back; unusual discoloration or bleeding; uncommon exhaustion; vomiting; yellowing of the skin or eyes.

This is not a complete list of all side effects that could take place. If you have questions concerning adverse effects, contact your healthcare service provider.

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