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Amigrenex is indicated for the acute therapy of migraine headache strikes with or without aura in adults. Amigrenex is a migraine medicine that narrows capillary around the mind. Amigrenex additionally reduces substances in the body that could set off migraine pain, nausea or vomiting, sensitivity to light and also audio, and other migraine headache signs and symptoms.


Usage Amigrenex precisely as suggested by your physician. Do not make use of in larger or smaller sized quantities or for longer compared to advised. Follow the instructions on your prescription label. Overuse of migraine frustration medication can really make your frustrations worse.

Use Amigrenex when you notice headache signs, or after a strike has already begun.

Your medical professional could want to give your very first dosage of this medication in a health center or clinic setting to see if you have any kind of serious negative effects.

Take one Amigrenex tablet whole with a complete glass of water. Do not split the tablet.

After taking a tablet: If your headache does not completely disappear, or goes away and also comes back, take a second tablet 2 (2) hours after the very first. Do not take more than 200 mg of sumatriptan dental tablets in 24-HOUR. If your signs and symptoms have actually not improved, contact your medical professional before taking anymore tablets.

Given that Amigrenex is utilized as needed, it does not have a day-to-day dosing schedule. Call your medical professional promptly if your signs and symptoms do not boost after using this medicine.

After taking a Amigrenex tablet, you should wait two (2) hrs prior to taking a 2nd tablet. Do not take more than 200 mg of sumatriptan tablets in 1 Day.

After using Amigrenex nasal spray, you need to wait two (2) hours before making use of a second spray. Do not utilize greater than 40 mg of nasal spray in 24 Hr.

Get in touch with your doctor if you have more than 4 migraines in one month (One Month).


In regulated professional tests, solitary dosages of 25, 50, or 100 mg of IMITREX Tablets were effective for the acute therapy of migraine headache in adults. There is proof that doses of 50 and 100 mg might provide a better impact than 25 mg.

The option of dosage ought to therefore be made on a private basis, evaluating the feasible benefit of a higher dose with the possibility for a greater danger of unfavorable occasions.

If the migraine returns or the individual has a partial response to the first dosage, the dosage could be repeated after 2 hrs, not to exceed an overall day-to-day dose of 200 mg.


Keep Amigrenex at area temperature away from dampness, warmth, and also light.

Do not make use of Amigrenex within 24 Hr prior to or after making use of one more migraine frustration medicine, including:

  • sumatriptan injection, almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig); or
  • ergot medicine such as dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (D.H.E. 45, Migranal), or methylergonovine (Methergine).

Amigrenex may harm your thinking or reactions. Beware if you drive or do anything that needs you to be alert.

You must not make use of Amigrenex if you are allergic to sumatriptan, or if you have:

  • coronary heart disease, angina (upper body pain), blood circulation troubles, absence of blood supply to the heart;
  • a history of heart problem, cardiac arrest, or stroke, consisting of "mini-stroke";
  • severe or unchecked hypertension;
  • serious liver disease;
  • ischemic bowel condition; or
  • a headache that seems various from your usual migraine headaches.

Do not use Amigrenex if you have actually utilized an MAO prevention such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days.

To make sure you could securely utilize Amigrenex, tell your medical professional if you have any of these various other conditions:

  • liver condition;
  • kidney condition;
  • epilepsy or various other seizure disorder;
  • high blood pressure, a heart rhythm problem; or
  • coronary heart disease (or risk factors such as diabetic issues, menopause, smoking cigarettes, being overweight, having high cholesterol, having a family history of coronary artery disease, being older compared to 40 and also a male, or being a female who has had a hysterectomy).

FDA pregnancy classification C. It is not known whether Amigrenex will harm a coming baby. Inform your doctor if you are expecting or plan to come to be expecting while using this drug. Sumatriptan can enter breast milk and also may hurt a nursing baby. Do not breast-feed within 12 hrs after using Amigrenex. If you use a bust pump during this moment, toss out any type of milk you gather. Do not feed it to your baby. Amigrenex should not be provided to anyone under 18 or over 65 years of age.

Obtain emergency medical aid if you have any one of these indicators of an allergy to Amigrenex: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop making use of Amigrenex and also call your doctor if you have a significant negative effects such as:

  • sensation of pain or rigidity in your jaw, neck, or throat;
  • breast discomfort or heavy sensation, discomfort infecting the arm or shoulder, nausea, sweating, general unwell feeling;
  • unexpected tingling or weakness, especially on one side of the body;
  • abrupt serious frustration, confusion, problems with vision, speech, or balance;
  • unexpected and also extreme stomach pain as well as bloody looseness of the bowels;
  • seizure (convulsions);
  • numbness or tingling and a pale or blue-colored look in your fingers or toes; or
  • (if you are additionally taking an antidepressant) - frustration, hallucinations, high temperature, rapid heart rate, over active reflexes, nausea or vomiting, vomiting, looseness of the bowels, loss of coordination, fainting.

Less severe Amigrenex adverse effects could include:

  • light frustration (not a migraine);
  • pressure or hefty sensation in any type of part of your body;
  • really feeling hot or chilly;
  • lightheadedness, rotating sensation;
  • drowsiness;
  • nausea, throwing up, drooling;
  • uncommon taste in your mouth after making use of the nasal spray;
  • burning, tingling, pain or other inflammation in your nose or throat after utilizing the nasal spray; or
  • heat, redness, or light tingling under your skin.

This is not a full list of negative effects and also others might take place. Call your physician for medical advice about negative effects.

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