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Bufexan (mesalamine delayed-release tablets) tablets are suggested for the therapy of slightly to reasonably active ulcerative colitis as well as for the maintenance of remission of ulcerative colitis.


Take this medicine specifically as directed by your physician. Do not take it more often, and also do not take it for a longer time than your doctor ordered. Also, do not quit taking this medicine without very first monitoring with your doctor.

Keep taking this medication for the full time of therapy, even if you begin to really feel better after a couple of days. Do not miss any type of doses.

You need to take the delayed-release tablets with food. All other brands of pills and tablets could be taken with or without food.

Ingest the capsule or tablet whole. Do closed, break, crush, or eat it prior to swallowing.

Do not change to another brand without talking to your medical professional. The number of capsules or tablets that you take relies on the brand name as well as stamina of the medicine. If you re-fill your medicine and also it looks different, talk to your pharmacist. One tablet of Bufexan® & reg; HD 800 milligrams (mg) tablet may not work similarly as two Bufexan® & reg; 400 mg tablets.

If you are taking the extended-release pill or the delayed-release tablet, component of the pill or tablet could pass into your feces after your body has taken in the medication. This is regular and also nothing to bother with.

If you miss out on a dose of this medicine, take it immediately. Nonetheless, if it is practically time for your following dosage, miss the missed out on dose as well as return to your routine application timetable. Do not double doses.


The dosage of this medicine will be various for various individuals. Follow your doctor's orders or the instructions on the label. The adhering to info consists of just the ordinary dosages of this medication. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take relies on the toughness of the medicine. Also, the number of dosages you take every day, the time permitted in between dosages, as well as the size of time you take the medication depend on the clinical problem for which you are using the medicine.

For the treatment of slightly to reasonably active ulcerative colitis:

The common dose in adults is two 400-mg tablets to be taken 3 times a day for a complete everyday dose of 2.4 grams for a period of 6 weeks.

For the upkeep of remission of ulcerative colitis:

The recommended dosage in adults is 1.6 grams daily, in split dosages. Treatment period in the possible, well-controlled test was 6 months.

2 Bufexan (mesalamine delayed-release tablets) 400 mg tablets have actually not been revealed to be bioequivalent to one Bufexan® & reg; HD( mesalamine )delayed-release 800 mg tablet.


Store the medicine in a closed container at space temperature, away from warmth, dampness, and direct light. Keep from cold.

Store the delayed-release tablets in a tightly-closed container to protect them from dampness. Placing desiccant bags in the container may likewise help to keep the tablets from obtaining damp.

Shut out of the reach of children.

Do not maintain outdated medication or medication not required.

In choosing to use a medicine, the risks of taking the medicine has to be weighed against the good it will do. This is a choice you as well as your physician will certainly make.

Before using Bufexan

Bufexan (mesalamine delayed-release tablets) tablets are contraindicated in people with hypersensitivity to salicylates or to any of the components of the Bufexan (mesalamine delayed-release tablets) tablet.

People with pyloric constriction may have prolonged gastric retention of Bufexan tablets which might postpone launch of mesalamine in the colon.

Worsening of the signs and symptoms of colitis has been reported in 3% of Bufexan (mesalamine delayed-release tablets) -treated individuals in regulated clinical tests. This acute response, characterized by cramping, abdominal discomfort, bloody diarrhea, and sometimes by fever, migraine, malaise, pruritus, rash, and also conjunctivitis, has actually been reported after the initiation of Bufexan tablets along with various other mesalamine products. Symptoms typically abate when Bufexan (mesalamine delayed-release tablets) tablets are stopped.

Some patients who have experienced a hypersensitivity reaction to sulfasalazine may have a similar reaction to Bufexan tablets or to various other compounds which consist of or are transformed to mesalamine.

It is important that your doctor check your development at normal visits. This will certainly permit your physician to see if the medicine is working appropriately as well as to make a decision if you must remain to take it. Pee or blood tests may be had to check for undesirable results.

Check with your medical professional right now if you have abdominal or tummy pain, bloody looseness of the bowels, cramps, fever, headache, or a breakout while you are using this medication. These might be signs and symptoms of a problem called mesalamine-induced severe intolerance syndrome.

Do not take antacids (e.g., Amphojel®& reg;, Maalox & reg;, Mylanta & reg;, Tums & reg;-RRB- while you are taking the Apriso™ & profession; extended-release pills. Utilizing these medications together might transform the amount of medicine that is launched in the body.

Tell your doctor if you have had an allergy to sulfasalazine (Azulfidine®& reg;-RRB-.

Do not take other medicines unless they have actually been discussed with your medical professional. This consists of prescription or nonprescription (over the counter medicines and also natural or vitamin supplements.

Together with its required results, a medication may trigger some unwanted impacts. Although not all these side effects could take place, if they do happen they may require medical focus.

Consult your medical professional quickly if any one of the adhering to negative effects take place:

A lot more typical:

  • Stomach or belly pain (severe)
  • bloody looseness of the bowels
  • rectal bleeding

Much less common:

  • Abdominal or stomach aches (serious)
  • obscured vision
  • wooziness
  • fever
  • full or puffed up sensation
  • frustration (severe)
  • anxiety
  • pounding in the ears
  • stress in the belly
  • skin breakout and itching
  • slow-moving or rapid heartbeat
  • swelling of the stomach or stomach area
  • uncommon fatigue or weak point


  • Anxiousness
  • neck and back pain (severe)
  • blue or pale skin
  • chest discomfort, potentially moving to the left arm, neck, or shoulder
  • chills
  • nausea or vomiting
  • shortness of breath
  • yellow eyes or skin

Get emergency aid quickly if any of the following symptoms of overdose take place:

  • Complication
  • deep or rapid breathing with wooziness
  • diarrhea (severe or continuing)
  • hard or struggled breathing
  • lightheadedness or lightheadedness
  • sleepiness (extreme)
  • feeling of continuous movement of self or environments
  • headache (extreme or proceeding)
  • hearing loss or ringing or humming in the ears (proceeding)
  • nausea or vomiting or throwing up (proceeding)
  • tingling of the feet, hands, and around the mouth
  • seizures
  • sensation of rotating
  • sweating
  • rigidity in the upper body
  • wheezing

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