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Hydroxyurea is utilized to deal with skin cancer cells (cancer malignancy), a cancer of the white blood cells called persistent myelocytic leukemia (CML), and also metastatic cancer (cancer that has actually spread) of the ovaries. This medication may additionally be given together with radiation treatment for head and also neck cancer (key squamous cell cancer).
Hydroxyurea is additionally made use of in grown-up people with sickle cell anemia to stop unpleasant episodes as well as decrease the requirement for blood transfusions. It works by making the red blood cells extra flexible.


Prior to you begin treatment with hydroxyurea, you as well as your physician should talk about the good this medication will certainly do in addition to the threats of using it.

Take this medicine precisely as directed by your medical professional. Do not make use of more of it, do not use it more frequently, as well as do not utilize it for a longer time compared to your physician gotten.

This medicine includes a person info insert. Read and also comply with the instructions in the insert very carefully. Ask your medical professional if you have any kind of concerns.

Hydroxyurea ought to be handled with treatment and also individuals that are not taking this medication must take care to avoid touching it. To lower the opportunity of touching the medicine:
Use disposable handwear covers when taking care of hydroxyurea or bottles including hydroxyurea.
Laundry your hands prior to and after contact with the container or capsules.
If powder from the pill is spilled, you must wipe it up quickly with a moist disposable towel and also discard it in a shut container, such as a plastic bag.
You must keep medication away from kids and pet dogs.
You need to contact your physician for guidelines on ways to throw away pills that are past the expiry date.

If you miss out on a dose of this medication, take it as soon as possible. However, if it is virtually time for your next dosage, skip the missed dose and return to your regular dosing timetable. Do not double doses.


The dosage of this medicine will be different for different individuals. Follow your physician's orders or the instructions on the tag. The complying with information consists of just the average dosages of this medicine. If your dose is different, do not alter it unless your doctor tells you to do so.

The quantity of medicine that you take depends upon the stamina of the medication. Also, the variety of dosages you take daily, the moment allowed between dosages, and also the size of time you take the medication rely on the clinical trouble for which you are making use of the medicine.
For oral dose kind (capsules):
For cancer cells of the head as well as neck, ovaries, or skin:

  • Grownups—-- Dosage is based on body weight and also have to be identified by your medical professional. The dose is 80 milligrams (mg) each kg (kg) of body weight, taken as a solitary dosage every 3rd day.
  • Youngsters—-- Usage and also dosage should be figured out by your physician.

For chronic myelocytic leukemia (CML):

  • Adults—-- Dose is based on body weight and also must be determined by your medical professional. The dosage is 30 milligrams (mg) each kilo (kg) of body weight daily, taken as a single dose.
  • Kids—-- Usage and dosage must be established by your medical professional.

For sickle cell anemia:

  • Grownups—-- Dose is based on body weight and also should be figured out by your medical professional. The dose is 15 milligrams (mg) per kilogram (kg) of body weight daily, taken as a single dosage. Your medical professional could boost your dosage as required. Nevertheless, the dosage is normally not more than 35 mg per kg of body weight each day.
  • Youngsters—-- Use and dosage must be established by your medical professional.


Store the medicine in a closed container at room temperature, away from heat, moisture, as well as direct light. Avoid cold.

Keep out of the reach of youngsters.

Do not keep outdated medicine or medicine not required.

Ask your healthcare specialist just how you ought to deal with any medicine you do not use.

It is crucial that your doctor inspect your progress at regular check outs to earn certain that this medication is working properly. Blood tests could be had to look for unwanted effects.

See to it your medical professional understands if you are expectant before you use this medicine. Using this medicine while you are expecting can hurt your unborn infant. If you assume you have actually become pregnant while utilizing the medication, inform your doctor as soon as possible.

While you are being treated with hydroxyurea, as well as after you quit utilizing it, do not have any booster shots (injections) without your physician's authorization. Hydroxyurea might reduce your body's resistance and also there is a chance you could obtain the infection the vaccination is indicated to stop. Additionally, various other persons staying in your family should not get live injections (eg, nasal flu vaccination, measles, mumps, or rubella) since there is a possibility they could pass the infection on you. Additionally, prevent individuals who have actually had an online vaccine. Do not obtain near them and do not stay in the same space with them for long. If you can not take these precautions, you should think about putting on a protective face mask that covers the nose as well as mouth.

Hydroxyurea can temporarily lower the number of white blood cells in your blood, raising the opportunity of getting an infection. It could additionally reduce the number of platelets, which are necessary for proper blood clot. If this happens, there are particular precautions you could take, particularly when your blood matter is low, to minimize the danger of infection or bleeding:

  • If you can, prevent individuals with infections. Check with your doctor quickly if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or uncomfortable or hard peeing.
  • Consult your physician quickly if you observe any type of uncommon blood loss or bruising; black, tarry feces; blood in the urine or stools; or determine red areas on your skin.
  • Beware when utilizing a routine tooth brush, dental floss, or toothpick. Your medical physician, dental professional, or registered nurse might advise other methods to clean your teeth as well as periodontals. Get in touch with your clinical physician before having any type of oral work done.
  • Do not touch your eyes or the within your nose unless you have actually simply cleaned your hands and also have not touched anything else in the meantime.
  • Take care not to cut on your own when you are making use of sharp things such as a safety and security razor or finger nail or nail cutters.
    Avoid get in touch with sporting activities or various other scenarios where bruising or injury could happen.

Using this medicine for a very long time might enhance your danger of creating cancer of the blood (leukemia). Speak to your medical professional if you have concerns about this risk.

This medication may trigger short-lived loss of hair in some individuals. After therapy has finished, normal hair growth need to return, although the new hair might be a somewhat different shade or texture.

Do not take various other medications unless they have been discussed with your medical professional. This includes prescription or nonprescription (over-the-counter medicines as well as herbal or vitamin supplements.

Along with its required results, a medication could trigger some undesirable impacts. Although not all of these adverse effects might happen, if they do happen they could require clinical focus.

Consult your medical professional quickly if any of the adhering to negative effects take place:
More usual

  • Cough or hoarseness
  • high temperature or chills
  • reduced back or side pain
  • painful or hard peeing

Much less usual

  • Black, tarry feces
  • blackening of the finger nails and nails
  • blood in the pee or feces
  • identify red spots on the skin
  • sores in the mouth and on the lips
  • uncommon blood loss or bruising


  • Confusion
  • convulsions (seizures)
  • difficulty with peeing
  • dizziness
  • migraine
  • joint pain
  • seeing, hearing, or feeling points that are not there
  • swelling of the feet or reduced legs

Occurrence unknowned

  • Bleeding under the skin
  • sores on the skin
  • blue or light shade on the skin of the fingers or toes
  • temperature of the fingers or toes
  • crater-like sores on the skin
  • itching skin
  • tingling or tingling of the fingers or toes
  • discomfort in the fingers or toes
  • unusual fatigue or weak point
  • fat burning

Obtain emergency assistance immediately

  • Signs and symptoms of overdose
  • Scaling of the skin on the hands as well as feet
  • severe eclipse of skin color
  • soreness
  • sores in the mouth as well as on the lips
  • swelling of the hands as well as soles of the feet
  • violet flushing of the skin

Some adverse effects could occur that normally do not need medical attention. These side effects might disappear throughout treatment as your body adjusts to the medication. Additionally, your healthcare expert might have the ability to inform you about means to stop or decrease several of these negative effects. Get in touch with your health care expert if any of the following negative effects proceed or are bothersome or if you have any kind of inquiries about them:
Extra common:

  • Diarrhea, sleepiness, loss of appetite, queasiness or throwing up.

Much less typical:

  • Irregular bowel movements, redness of skin at the area of irradiation, skin rash as well as irritation.

Other side impacts not provided could likewise take place in some people. If you observe other impacts, check with your health care expert.

Call your physician for clinical advice concerning adverse effects.

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