KARBIDOPA-LEVODOPA (SINEMET) INDICATIONSLevodopa is converted to a chemical called dopamine (DOE meen) in the mind. Symptoms of Parkinson's condition could be caused by reduced levels of dopamine in the brain.
Carbidopa helps prevent the malfunction of levodopa prior to it could reach the brain and also work.
The combination of carbidopa and levodopa is made use of to treat Parkinson signs and symptoms such as muscle mass rigidity, tremors, spasms, and also inadequate muscle control. This medicine is also made use of to treat Parkinson signs and symptoms brought on by carbon monoxide poisoning or manganese drunkenness.
Carbidopa and levodopa may also be made use of for various other objectives not noted in this medication guide.
KARBIDOPA-LEVODOPA (SINEMET) GUIDELINES
If you are currently taking levodopa (Larodopa, Dopar), you have to stop taking it at the very least 12 hrs before you start taking carbidopa as well as levodopa.
Take specifically as recommended by your physician. Do not absorb larger or smaller amounts or for longer than recommended. Comply with the instructions on your prescription label.
Carbidopa as well as levodopa could be taken with or without food. Take your doses at regular periods to keep a stable quantity of the drug in your body at all times.
The regular tablet can be broken or squashed if had to make it easier to swallow.
To take the by mouth breaking down tablet (Parcopa):
Maintain the tablet in its blister pack up until you prepare to take the medicine. Open the package and peel off back the aluminum foil from the tablet blister. Do not press a tablet via the aluminum foil or you may damage the tablet.
Utilizing completely dry hands, remove the tablet as well as location it in your mouth. It will begin to liquify immediately.
Do not swallow the tablet whole. Permit it to dissolve in your mouth without eating. Swallow numerous times as the tablet dissolves.
To ensure this medicine is assisting your condition and is not causing harmful effects, your blood will should be examined commonly. Your heart, liver, as well as kidney feature might likewise need to be tested. Visit your physician consistently.
This drug can trigger uncommon results with specific medical tests. Tell any kind of medical professional who treats you that you are using carbidopa and levodopa.
KARBIDOPA-LEVODOPA (SINEMET) STORAGE SPACE
Store at room temperature level away from moisture, warm, and light.
KARBIDOPA-LEVODOPA (SINEMET) EVEN MORE INFORMATION:
Active Component: Carbidopa and Levodopa
Do not take carbidopa and also levodopa if you have actually used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) within the previous 14 days. Significant, dangerous negative effects could take place if you take carbidopa and levodopa prior to the MAO prevention has gotten rid of from your body.
You should not take this medication if you dislike carbidopa (Lodosyn) or levodopa (Larodopa), or if you have:
unusual skin lesions that have actually not been inspected by a medical professional; or
a background of malignant melanoma (skin cancer cells).
If you have any of these other conditions, you might need a dose change or unique tests:
heart disease, hypertension, coronary artery disease, a heart rhythm problem, or a previous cardiac arrest;
asthma, persistent obstructive lung condition (COPD), or other breathing condition;
liver or kidney condition;
an endocrine (hormone) disease;
a belly or digestive tract ulcer;
wide-angle glaucoma; or
clinical depression or other mental disorder.
You could have enhanced sexual urges, unusual urges to wager, or other extreme prompts while taking carbidopa as well as levodopa. It is unknowned whether the medication really triggers this effect. Talk with your medical professional if you think you have any type of intense or uncommon urges while taking carbidopa and levodopa.
Some people taking medications for Parkinson's disease have created skin cancer cells (melanoma). Nonetheless, people with Parkinson's disease might have a higher danger than most individuals for establishing cancer malignancy. Talk with your physician regarding your particular threat and also just what skin signs and symptoms to look for. You could have to have normal skin exams.
The disintegrating tablet (such as Parcopa) might contain phenylalanine. Talk with your medical professional before utilizing this kind of carbidopa as well as levodopa if you have phenylketonuria (PKU).
If you missed the dose take it as soon as you remember. Avoid the missed dose if it is virtually time for your next set up dosage. Do not take additional medication making up the missed out on dose.
You could see that your sweat, urine, or saliva appears dark in shade, such as red, brown, or black. This is not a harmful adverse effects, but it could trigger discoloration of your garments or bed sheets.
agitated muscle activities in your eyes, tongue, jaw, or neck;
worsening of shakes (unchecked drinking);
high fever, tight muscular tissues, sweating, rapid or unequal heart beats, fast breathing, feeling like you may lose consciousness;
painful or tough urination;
severe nausea, throwing up, or looseness of the bowels;
irregular heart rate or trembling in your breast;
confusion, hallucinations, anxiety, anxiety, clinically depressed mood, ideas of self-destruction or harming yourself;
breast pain or hefty feeling, pain spreading to the arm or shoulder.
Less severe side effects may include:
light nausea or vomiting, dry mouth, anorexia nervosa, heartburn, diarrhea, constipation;
migraine, wooziness, sleepiness, obscured vision;
sneezing, stuffy nose, cough, or other cold symptoms;
rest problems (sleeping disorders), unusual dreams;
muscle mass pain, pins and needles or tingly feeling; or
skin rash or itching.
This is not a full list of adverse effects as well as others might take place. Call your physician for medical recommendations about side effects.